Vaccines for Covid 19

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Chris Wright
Posts: 131
Joined: Sun Nov 19, 2006 9:21 pm

Re: Vaccines for Covid 19

Post by Chris Wright »

Sue et al,

Just spoke to my GP who is reasonably clear that this is not a matter of concern.

As much as i understand it, the current antibody tests are designed to pick up signs that you have gained immunity from having had Covid.

They won't measure if you have had a T-Cell response from the vaccine which can give you some immunisation.

Having said that, she's arranging for me to have a test 3 weeks after my second shot, so end April basically.

By then, there will be far more data about what is happening re: vaccines and immunocompromised patients and we will better know if i immunised or if not, how to proceed.

Again, hope that helps.

C
Transplanted Sept 1981

Still enjoying life like a 21 year old, or younger!
Thumps
Posts: 1244
Joined: Thu Sep 14, 2006 3:50 pm
Location: London, England

Re: Vaccines for Covid 19

Post by Thumps »

When you say your GP is arranging for you to have a test, what kind of test do you mean? An antibody test?

My second shot is also mid-April, wondering if there's a way i can do the same.
PKD/PLD diagnosed 1994, CKD stage 5 Oct 2007, Living Donor Kidney Transplant Dec 2008, still going strong!
Chris Wright
Posts: 131
Joined: Sun Nov 19, 2006 9:21 pm

Re: Vaccines for Covid 19

Post by Chris Wright »

Yep, but when i spoke to my renal unit, they also said i could have it done there.
Transplanted Sept 1981

Still enjoying life like a 21 year old, or younger!
morzov
Posts: 19
Joined: Thu Jul 23, 2009 7:52 pm

Re: Vaccines for Covid 19

Post by morzov »

Interesting to read about people's experiences and views and that the emphasis is now moving to efficacy - in other words to what extent are we protected. That leads onto the question of what we would feel comfortable doing.

My take on this is that there are general studies taking place such as the OCTAVE trial but results won't be available for some time. Incidentally I tried to get on the OCTAVE trial in March when it had or was about to start but they said too late if you have already had vaccine. I pointed out that nearly all the CEV group had been vaccinated before 14 Feb i.e. the people they needed to go through the trial weren't eligible!

The other approach is to get an individualised antibody test. I lloked into this with an organisation called Tests4all or something like that but again as pointed out earlier these tests - which I understand were manufactured by Roche - are primarily for identifying antibodies developed as a result from infection. Thereafter I don't know enough about the science but I didn't go ahead.

So it's interesting to now read that some GPs and units are offering to do individualised tests. Be very interested to hear more details on that. Pretty sure my own unit will not be doing anti body tests - they have not even recorded which vaccine I had and when even though I volunteered the info. But if it is happening elsewhere then I will press them to do it.

Sorry if this doesn't really offer any great hope but I think we just all have to be careful until we have a better idea of what level of protection we have. For example I think I would be OK having a drink in a pub outside but I would not eat or drink inside basically because I would not feel comfortable without a mask. But then my eGFR is only low 30s so maybe I'm ultra cautious.
Thumps
Posts: 1244
Joined: Thu Sep 14, 2006 3:50 pm
Location: London, England

Re: Vaccines for Covid 19

Post by Thumps »

I also pointed out to the OCTAVE researchers that they'd left their recruitment rather too late, but I suspect they were tied up in ethics forms. Real shame.

I'm so frustrated that we're hearing nothing about possible efficacy for us. I'm hearing news about over 70s and cancer patients but nothing at all about transplant patients. I wrote to my renal team about the possibility of antibody tests or similar, so far heard absolutely nothing back, not even a 'no'.

In terms of risk profile... I think I'll probably steer clear of closed indoor places for a while yet, but I'm going to hug my loved ones who have also been vaccinated when we're all in that position and trust my loved ones to be careful, as I've had to do ever since I got my actual transplant!
PKD/PLD diagnosed 1994, CKD stage 5 Oct 2007, Living Donor Kidney Transplant Dec 2008, still going strong!
morzov
Posts: 19
Joined: Thu Jul 23, 2009 7:52 pm

Re: Vaccines for Covid 19

Post by morzov »

Spotted this online today. Study in the USA of SOT patients who have had one dose of Pfizer or Moderna vaccine and antibody response.

https://twitter.com/mkwillicombe/status ... 9475227656

Results are not great.
Thumps
Posts: 1244
Joined: Thu Sep 14, 2006 3:50 pm
Location: London, England

Re: Vaccines for Covid 19

Post by Thumps »

Oh no. That is not good reading.
PKD/PLD diagnosed 1994, CKD stage 5 Oct 2007, Living Donor Kidney Transplant Dec 2008, still going strong!
Thumps
Posts: 1244
Joined: Thu Sep 14, 2006 3:50 pm
Location: London, England

Re: Vaccines for Covid 19

Post by Thumps »

So - had my second dose of vaccine brought forward, had it on Thursday. Properly knocked me back for about 3 days.

Good news is I did a private antibody test the day before my second dose and it looks like i've had a reasonably strong reaction to the first dose of vaccine which is great!
PKD/PLD diagnosed 1994, CKD stage 5 Oct 2007, Living Donor Kidney Transplant Dec 2008, still going strong!
Skm
Posts: 40
Joined: Sat Sep 01, 2018 10:13 am

Re: Vaccines for Covid 19

Post by Skm »

Thumps,

Which vaccine did you have? (I’m impressed with your antibody result).
Still awaiting my AZ booster. I’d love to know if it has worked.

Sue
Transplant May 2015
Thumps
Posts: 1244
Joined: Thu Sep 14, 2006 3:50 pm
Location: London, England

Re: Vaccines for Covid 19

Post by Thumps »

I had Pfizer, and I also chose to take the calculated risk of cutting back my immunosuppressants by half the week after I had the jab (basically cutting out my evening doses) to give my immune system a fighting chance. I am NOT suggesting anyone should do this - it was a personal choice based on previous experiences of being asked to cut certain drugs while recovering from illness and having a very stable transplant. I've no idea if that's the reason I seem to be doing ok. I was asked whether I had previously had the virus or been exposed - all I can say is that if i've had it or been exposed to it, it was in an entirely asymptomatic way!
PKD/PLD diagnosed 1994, CKD stage 5 Oct 2007, Living Donor Kidney Transplant Dec 2008, still going strong!
Skm
Posts: 40
Joined: Sat Sep 01, 2018 10:13 am

Re: Vaccines for Covid 19

Post by Skm »

Thumps,

That’s very interesting. I don’t think I’m brave enough to reduce my immunosuppression like that. I may discuss with my consultant next time I see him (these telephone appointments just aren’t the same). It does seem a good idea. Like you my transplant seems very stable.
I’ve just (an hour ago) had my AZ booster.

Sue
Transplant May 2015
Chris Wright
Posts: 131
Joined: Sun Nov 19, 2006 9:21 pm

Re: Vaccines for Covid 19

Post by Chris Wright »

For what it's worth guys, i received a letter today saying that "My adult household contacts are now eligible to receive the COVID-19 vaccination."

This is because they are living with someone with "severe immunosuppression".

Gotta arrange through my GP.

C
Transplanted Sept 1981

Still enjoying life like a 21 year old, or younger!
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